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蛋白质/抗原/多肽 >> 重组蛋白
重组胞质分裂作用因子3(DOCK3)蛋白
重组胞质分裂作用因子3(DOCK3)蛋白图片
交货期: 1周
索取资料及报价
交货期:1周
产品别名:重组视神经细胞相关蛋白/早老素结合蛋白
Recombinant DOCK3
产品介绍
基因名:

DOCK3


产品别名:

MOCA; NEDIDHA; PBP; DOCK3; dedicator of cytokinesis 3; dedicator of cytokinesis 3; dedicator of cytokinesis protein 3; modifier of cell adhesion; presenilin-binding protein; 胞质分裂作用因子3(DOCK3); 视神经细胞相关蛋白/早老素结合蛋白;


背景信息:
MOCA (modifier of cell adhesion), also known as Presenilin-binding protein (PBP) or dedicator of cytokinesis protein 3 (DOCK3), is a 2030 amino acid cytoplasmic protein belonging to the DOCK family. MOCA interacts with Presenilin proteins and has the ability to stimulate Tau phosphorylation suggesting that MOCA may be involved in Alzheimer disease. MOCA is also thought to be a guanine nucleotide exchange factor (GEF) which activates small GTPases by exchanging bound GDP for free GTP. Analysis of ectopic expression suggests that MOCA may affect the function of small GTPases involved in the regulation of Actin cytoskeleton or cell adhesion receptors. MOCA is localized to the neuropil, and sometimes in pyramidal cells, in normal brains, while in Alzheimer disease brains, MOCA is present in neurofibrillary tangles.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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