产品介绍 基因名： FARSA 产品别名： CML33； FARSL； FARSLA； FRSA； PheHA； RILDBC2； FARSA； phenylalanyl-tRNA synthetase subunit alpha； phenylalanyl-tRNA synthetase subunit alpha； phenylalanine--tRNA ligase alpha subunit； pheRS； phenylalanine tRNA ligase 1, alpha, cytoplasmic； phenylalanine--tRNA ligase alpha chain； phenylalanine-tRNA synthetase alpha-subunit； phenylalanine-tRNA synthetase-like, alpha subunit； phenylalanyl-tRNA synthetase alpha chain； phenylalanyl-tRNA synthetase alpha subunit； phenylalanyl-tRNA synthetase-like, alpha subunit； 慢性粒细胞白血病33； 苯丙氨酰tRNA合成酶α(FARSa)； 背景信息： Aminoacyl-tRNA synthetases consist of a family of enzymes that catalyze the specific aminoacylation of tRNA by their cognate amino acid in the initial step of ribosome-dependent protein biosynthesis. FARSLA, also known as FRSA, CML33, FARSL or PheHA (phenylalanyl-tRNA synthetase, alpha subunit), is a member of the class-II aminoacyl-tRNA synthetase family and is highly expressed in proliferating cells of bone marrow. FARSLA is a cytoplasmic phenylalanine-tRNA synthetase that functions as a heterodimer consisting of a catalytic alpha-subunit and a regulatory beta-subunit. The alpha-subunit is responsible for forming the amino acid binding pocket, mediating the ATP/aminoacyl adenylate binding, and interacts with the acceptor stem of the tRNA. FARSLA functions in a cell cycle-dependent and differentiation-dependent manner. 标签：His-tag |
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