产品介绍 基因名: KIR2DL2 产品别名: CD158B1; CD158b; NKAT-6; NKAT6; p58.2; KIR2DL2; killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 2; killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 2; killer cell immunoglobulin-like receptor 2DL2; CD158 antigen-like family member B1; MHC class I NK cell receptor; killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2; natural killer-associated transcript 6; p58 NK receptor CL-43; p58 natural killer cell receptor clone CL-43; NK细胞抑制性受体2DL2; 杀伤细胞免疫球蛋白样受体2DL2(KIR2DL2); 背景信息: KIR2DL2 (2DL2, formerly NKAT6, designated CD158b) is a 348 amino acid (aa) type I transmembrane glycoprotein that belongs to the human killer cell Ig?like receptor (KIR) family. KIRs are expressed on human CD56dim NK cells and T cell subsets, and regulate effector functions in the innate immune system.KIR2DL2 is receptor on natural killer (NK) cells for HLA-Cw1, 3, 7, and 8 allotypes. Inhibits the activity of NK cells thus preventing cell lysis. 标签:His-tag |
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