蛋白质/抗原/多肽 >> 重组蛋白
重组DNA结合蛋白κB
产品介绍 基因名: NFRKB 产品别名: INO80G; NFRKB; nuclear factor related to kappaB binding protein; nuclear factor related to kappaB binding protein; nuclear factor related to kappa-B-binding protein; DNA-binding protein R kappa B; INO80 complex subunit G; DNA结合蛋白κB; 核因子相关κB结合蛋白(NFRkB); 背景信息: DNA-binding protein R kappa-B, is a nuclear protein that binds to the DNA consensus sequence 5'-GGGGAATCTCC-3' of NF kappa B. Binding of NFR kappa B is thought to regulate IL-2R alpha (interleukin-2 receptor alpha-chain) gene expression, a critical step in T-cell activation. NFR kappa B exists as 3 isoforms due to alternative splicing and is expressed primarily in the brain, liver, spleen, testis and thymus NFR kappa B gene expression is amplified in acute myeloid leukemia, suggesting a possible role in carcinogenesis. 标签:His-tag |
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