产品介绍 基因名: PGGT1B 产品别名: BGGI; GGTI; PGGT1B; protein geranylgeranyltransferase type I subunit beta; protein geranylgeranyltransferase type I subunit beta; geranylgeranyl transferase type-1 subunit beta; CTC-428G20.3; GGTase-I-beta; geranylgeranyl transferase type I subunit beta; geranylgeranyltransferase type I beta subunit; protein geranylgeranyltransferase type I, beta subunit; type I protein geranyl-geranyltransferase subunit beta; 蛋白牻牛儿基牻牛儿基转移酶Ⅰβ(PGGT1b); 香叶烯基转移酶1β; 背景信息: Protein geranylgeranyltransferase type I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a C-terminal CAAX motif in which 'A' is an aliphatic amino acid and 'X' is leucine (summarized by Zhang et al., 1994 [PubMed 8106351]). The enzyme is composed of a 48-kD alpha subunit (FNTA; MIM 134635) and a 43-kD beta subunit, encoded by the PGGT1B gene. The FNTA gene encodes the alpha subunit for both GGTase-I and the related enzyme farnesyltransferase.[supplied by OMIM, Mar 2010] 标签:His-tag |
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