蛋白质/抗原/多肽 >> 重组蛋白
重组调节因子X结合蛋白RFXAP
产品介绍 基因名: RFXAP 产品别名: RFXAP; regulatory factor X associated protein; regulatory factor X associated protein; regulatory factor X-associated protein; RFX DNA-binding complex 36 kDa subunit; RFX-associated protein; 调节因子X结合蛋白RFXAP; 背景信息: Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated ankyrin-containing protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group D. Transcript variants utilizing different polyA signals have been found for this gene. [provided by RefSeq, Jul 2008] 标签:His-tag |
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