蛋白质/抗原/多肽 >> 重组蛋白
重组非红细胞血影脑蛋白β2/spectrinβIII
产品介绍 基因名: SPTBN2 产品别名: GTRAP41; SCA5; SCAR14; SPTBN2; spectrin beta, non-erythrocytic 2; spectrin beta, non-erythrocytic 2; spectrin beta chain, non-erythrocytic 2; beta-III spectrin; glutamate transporter EAAT4-associated protein 41; spectrin beta III sigma 2; spectrin beta chain, brain 2; spectrin, non-erythroid beta chain 2; spinocerebellar ataxia 5 protein; 非红细胞血影脑蛋白β2/spectrinβIII; 背景信息: Spectrin is an actin binding protein that is a major component of the plasma membrane skeleton. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Spectrin Alpha and spectrin Beta are present in erythrocytes, whereas spectrin Alpha II (also designated fodrin Alpha) and spectrin Beta I (also designated fodrin Beta) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Spectrin Beta III is highly homologous to both spectrin Beta I and spectrin Beta II. Western blot analysis shows that spectrin Beta III migrates at a higher molecular mass than predicted in the kidney. Spectrin Beta III is highly expressed in brain, kidney, pancreas, and liver, and at lower levels in lung and placenta. Specifically, spectrin Beta III constitutes a major component of the Golgi and vesicular membrane skeletons. 标签:His-tag |
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