产品介绍 基因名: XK 产品别名: KX; NA; NAC; X1k; XKR1; XK; X-linked Kx blood group antigen, Kell and VPS13A binding protein; X-linked Kx blood group antigen, Kell and VPS13A binding protein; endoplasmic reticulum membrane adapter protein XK; membrane transport protein XK; Kell blood group precursor (McLeod phenotype); Kx antigen; Kx blood group antigen; XK, Kell blood group complex subunit (McLeod syndrome); XK-related protein 1; kell complex 37 kDa component; 膜转运蛋白XK; 背景信息: XK is the Kell blood group 'precursor substance'. This protein has structural characteristics of prokaryotic and eukaryotic membrane transport proteins. The Kell blood group is constituted by two covalently linked antigens at the surface of red blood cells, Kell and KX. Whereas Kell is a metalloprotease with demonstrated in vitro enzymatic activity, the role of KX thereon, and/or alone, remains unknown, although its absence is linked to the McLeod syndrome, a neuroacanthocytosis. KX appears to be required for proper synthesis or presentation of the Kell antigens on the red blood cell surface. 标签:His-tag |
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