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蛋白质/抗原/多肽 >> 重组蛋白
重组淋巴细胞抗原Ly6D蛋白
重组淋巴细胞抗原Ly6D蛋白图片
交货期: 1周
索取资料及报价
交货期:1周
产品别名:Recombinant LY6D
Recombinant lymphocyte antigen 6 family member D protein
产品介绍
基因名:

LY6D


产品别名:

E48; Ly-6D; LY6D; lymphocyte antigen 6 family member D; lymphocyte antigen 6 family member D; lymphocyte antigen 6D; e48 antigen; lymphocyte antigen 6 complex, locus D; 淋巴细胞抗原Ly6D;


背景信息:
Ly-6D is a 128 amino acid glycoprotein that is expressed in squamous cell carcinoma cell lines and squamous cell epithelia tissue. Ly-6D contains a signal peptide, 2 theoretical phosphorylation sites and 3 putative myristoylation sites. Upregulation of the gene encoding Ly-6D in head and neck cancers is associated with poor prognosis and high expression of Ly-6D has been linked to enhanced cell migration. Ly-6D is frequently used as a molecular marker for diagnosis and therapy of head-and-neck squamous cell carcinoma (HNSCC). It has been suggested that Ly-6D may regulate the expression levels of certain fucosylated E-selectin ligands and protein FX, a protein that contributes to the last step in the synthesis of GDP-L-fucose, in HNSCC cell lines. This finding is indicative that Ly-6D may regulate tumor cell adhesion in inflamed vessel walls that express E-selectin.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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