蛋白质/抗原/多肽 >> 重组蛋白
重组中心体蛋白104
产品介绍 基因名: CEP104 产品别名: CFAP256; GlyBP; JBTS25; KIAA0562; ROC22; CEP104; centrosomal protein 104; centrosomal protein 104; centrosomal protein of 104 kDa; centrosomal protein 104kDa; 中心体蛋白104; 甘氨酸结合蛋白; 背景信息: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The KIAA0562 gene product has been provisionally designated KIAA0562 pending further characterization. 标签:His-tag |
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