蛋白质/抗原/多肽 >> 重组蛋白
重组LRIG2蛋白
产品介绍 基因名: LRIG2 产品别名: LIG-2; LIG2; UFS2; LRIG2; leucine rich repeats and immunoglobulin like domains 2; leucine rich repeats and immunoglobulin like domains 2; leucine-rich repeats and immunoglobulin-like domains protein 2; 背景信息: LRIG2 is produced in all human glioma cell lines and localizes to perinuclear compartments, cytoplasmic compartments and the cell surface. It acts as a negative feedback regulator of signaling through enhanced receptor ubiquitination and accelerated intracellular degradation. LRIG2 may function as a tumour suppressor since it downregulates the expression of EGF and the related proteins ErbB-2, ErbB-3 and ErbB-4, which all inhibit cancer cells from growth, migration and invasion. 标签:His-tag |
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