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蛋白质/抗原/多肽 >> 重组蛋白
重组半胱氨酸蛋白酶8相关蛋白2
重组半胱氨酸蛋白酶8相关蛋白2图片
交货期: 1周
索取资料及报价
交货期:1周
产品别名:重组胱天蛋白酶8关联蛋白2(CASP8AP2)
Recombinant CASP8AP2
产品介绍
基因名:

CASP8AP2


产品别名:

CED-4; FLASH; RIP25; CASP8AP2; caspase 8 associated protein 2; caspase 8 associated protein 2; CASP8-associated protein 2; FLASH homolog RIP25; FLICE associated huge; FLICE-associated huge protein; human FLASH; 半胱氨酸蛋白酶8相关蛋白2; 胱天蛋白酶8关联蛋白2(CASP8AP2);


背景信息:
FLASH is involved in Fas induced apoptosis. It is recruited to Fas after the receptor cross-linking. Overexpression of wild type of FLASH facilitates and its dominant negative form inhibits Fas induced apoptosis. FLASH interacts with the DEDs of caspase-8 and FADD through the DED-like domain of FLASH and mediates activation of caspase-8. There are parallels between FLASH and Apaf-1/CED-4 although there are arguments against their structural similarity.
Studies of FLASH protein suggested that this protein may be a component of the death inducing signaling complex that includes Fas receptor, Fas binding adapter FADD, and caspase 8, and plays a regulatory role in Fas mediated apoptosis.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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