蛋白质/抗原/多肽 >> 重组蛋白
重组FBXW10蛋白
产品介绍 基因名: FBXW10 产品别名: Fbw10; HREP; SM25H2; SM2SH2; FBXW10; F-box and WD repeat domain containing 10; F-box and WD repeat domain containing 10; F-box/WD repeat-containing protein 10; F-box and WD-40 domain protein 10; testicular tissue protein Li 69; ubiquitin ligase specificity factor; FBXW10蛋白; 背景信息: F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular processes, including the cell cycle, immune responses, signaling cascades and developmental events, through the targeting of proteins, such as cyclins, cyclin-dependent kinase inhibitors, I˚B-å and ∫-catenin, for proteasomal degradation. FBXW10 (F-box and WD repeat domain containing 10), also known as protein Ubiquitin ligase-specificity factor, is a 1,052 amino acid protein that contains one F-box domain and seven WD repeats. Existing as four alternatively spliced isoforms, FBXW10 induces degradation of CBX5 and CBX1. 标签:His-tag |
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