产品介绍 基因名： GCN1 产品别名： GCN1L； GCN1L1； PRIC295； GCN1； GCN1 activator of EIF2AK4； GCN1 activator of EIF2AK4； eIF-2-alpha kinase activator GCN1； GCN1 (general control of amino-acid synthesis 1, yeast)-like 1； GCN1 eIF-2-alpha kinase activator homolog； GCN1 general control of amino-acid synthesis 1-like 1； GCN1, eIF2 alpha kinase activator homolog； GCN1-like protein 1； general control of amino-acid synthesis 1-like protein 1； hsGCN1； peroxisome proliferator activated receptor interacting complex protein； translational activator GCN1； 广泛控制氨基酸合成1样蛋白1； 背景信息： GCN1L1 is a 2,671 amino acid protein that is ubiquitously expressed and belongs to the GCN1 family. Functioning as a translation activator, GCN1L1 interacts with IMPACT to regulproteinate GCN2 kinase activity. GCN1L1 contains 24 HEAT repeats and is encoded by a gene that maps to human chromosome 12q24.23. Chromosome 12 encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders. 标签：His-tag |
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