蛋白质/抗原/多肽 >> 重组蛋白
重组细胞色素P450 1A1蛋白
产品介绍 基因名: Ahrr 产品别名: mKIAA1234; Ahrr; aryl-hydrocarbon receptor repressor; aryl-hydrocarbon receptor repressor; aryl hydrocarbon receptor repressor; ahR repressor; 细胞色素P450 1A1; 芳烃受体抑制因子(AHRR); 背景信息: The Cytochrome P450 (P450) superfamily of enzymes is one of three enzyme systems which metabolize the fatty acid arachadonic acid (AA) to regulators of vascular tone. P450 enzymes are monooxygenase enzymes which require several cofactors such as nicotinamide adenine dinucleotide phosphate (NADPH) and P450 reductase. There are over 200 known genes which encode P450s. Epoxygenases are those P450s which metabolize AA to epoxyeicosatrienoic acid (EETs) and omega hydroxylases are those P450s which produce 19- and 20-hydroxyeicosatetraenoic acids (19- and 20-HETE). As well as fatty acid metabolism, P450s also metabolize many drugs and toxins. Cytochrome P450 3A4 is abundantly expressed in liver and small intestine and is inducible by barbiturates, glucocorticoids and rifampicin. 标签:His-tag |
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