蛋白质/抗原/多肽 >> 重组蛋白
重组Ccl21a蛋白
产品介绍 基因名: Ccl21a 产品别名: 6CKBAC2; 6Ckine; ALP; AW987545; CKb9; Gm1987; SCYA21a; SLC; Scya21; Scya21b; Tca4; plt; Ccl21a; chemokine (C-C motif) ligand 21A (serine); chemokine (C-C motif) ligand 21A (serine); C-C motif chemokine 21a; CC chemokine 6Ckine-ser; CCL21-Ser; beta-chemokine exodus-2; exodus-2; small inducible cytokine A21a; thymus-derived chemotactic agent 4; 背景信息: C-C Motif Chemokine 21a (CCL21a) is a small secreted cytokine that belongs to the intercrine beta (CC chemokine) family. Mouse CCL21 cDNA encodes a 133 amino acid residue protein with a 23 residue signal peptide that is cleaved to generate the 110 residue mature protein. Mouse CCL21 has three forms while CCL21a has Ser-65. CCL21 elicits its effects by binding to a cell surface chemokine receptor known as CCR7 and CXCR3. Mouse CCL21 inhibits hemopoiesis and stimulates chemotaxis. It has chemotactic function in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Mouse CCL21 shows preferential activity towards naive T-cells and may play a role in mediating homing of lymphocytes to secondary lymphoid organs. 标签:His-tag |
相关产品
|