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蛋白质/抗原/多肽 >> 重组蛋白
重组肌萎缩侧索硬化症相关蛋白4
重组肌萎缩侧索硬化症相关蛋白4图片
交货期: 1周
索取资料及报价
交货期:1周
产品别名:Recombinant SETX
Recombinant senataxin protein
产品介绍
基因名:

SETX


产品别名:

ALS4; AOA2; SCAN2; SCAR1; STEX; Sen1; bA479K20.2; SETX; senataxin; senataxin; probable helicase senataxin; SEN1 homolog; amyotrophic lateral sclerosis 4 protein; 肌萎缩侧索硬化症相关蛋白4;


背景信息:
SETX belongs to the DNA2/NAM7 helicase family. Localizing to the nucleolus or the nucleoplasm in a cell cycle-dependent manner and to the cytoplasm, SETX contains a C-terminal DNA/RNA helicase domain and is believed to function as a helicase involved in RNA processing and DNA repair. Mutations in the gene encoding SETX can lead to ataxia-ocular apraxia 2 (AOA2) or amyotrophic lateral sclerosis 4 (ALS4). AOA2, also known as spinocerebellar ataxia-1 (SCAR1), is an autosomal recessive disorder characterized by progressive neurodegeneration of the cerebellum associated with the loss of Purkinje cells. ALS4 is a familial childhood- or adolescent-onset neurodegenerative disorder affecting both upper and lower motor neurons that ultimately results in fatal paralysis.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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