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蛋白质/抗原/多肽 >> 重组蛋白
重组减数分裂蛋白SPO11
重组减数分裂蛋白SPO11图片
交货期: 1周
索取资料及报价
交货期:1周
产品别名:Recombinant SPO11
Recombinant SPO11 initiator of meiotic double stranded breaks protein
产品介绍
基因名:

SPO11


产品别名:

CT35; SPATA43; TOPOVIA; TOPVIA; SPO11; SPO11 initiator of meiotic double stranded breaks; SPO11 initiator of meiotic double stranded breaks; meiotic recombination protein SPO11; SPO11 meiotic protein covalently bound to DSB homolog; cancer/testis antigen 35; spermatogenesis associated 43; 减数分裂蛋白SPO11;


背景信息:
Spo11 is a type II topoisomerase that is thought to generate the chromosome breaks that initiate meiotic recombination. The Spo11 protein initiates meiotic recombination by generating DNA double-strand breaks (DSBs) and is required for meiotic synapsis in S. cerevisiae. The DSBs are located mostly in promoter regions, where the chromatin is in an open configuration, and cluster in domains along the chromosome. Expression of the Spo11 is detected mainly in the testis, in agreement with its predicted function in the initiation of meiotic recombination. Disruption of Spo11 leads to severe gonadal abnormalities from defective meiosis and results in infertility.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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