蛋白质/抗原/多肽 >> 重组蛋白
重组垂体瘤细胞凋亡蛋白
产品介绍 基因名: RHBDD3 产品别名: C22orf3; HS984G1A; PTAG; RHBDD3; rhomboid domain containing 3; rhomboid domain containing 3; rhomboid domain-containing protein 3; hypothetical protein HS984G1A; pituitary tumor apoptosis; 垂体瘤细胞凋亡; 背景信息: PTAG is a novel 386 amino acid multi-pass membrane protein that contains one UBA domain and augments drug-induced apoptosis. Cells lacking PTAG have a reduced apoptotic response, thereby causing a predisposition to cell malignancy and resistance to chemotherapeutic interventions, and PTAG plays a role in colorectal tumorigenesis as the majority of primary colorectal tumors lack the PTAG gene. Encoded by a gene located on human chromosome 22, PTAG is often co-expressed with EWS (ewing sarcoma breakpoint region 1), a gene located directly downstream of PTAG. 标签:His-tag |
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