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蛋白质/抗原/多肽 >> 重组蛋白
重组FGD2蛋白
重组FGD2蛋白图片
交货期: 1周
索取资料及报价
交货期:1周
产品别名:Recombinant Fgd2
Recombinant FYVE, RhoGEF and PH domain containing 2 protein
产品介绍
基因名:

Fgd2


产品别名:

Tcd-2; Tcd2; ZFYVE4; tcs-2; tcs2; Fgd2; FYVE, RhoGEF and PH domain containing 2; FYVE, RhoGEF and PH domain containing 2; FYVE, RhoGEF and PH domain-containing protein 2; Fgd1 family, member 2; Fgd2-like protein; faciogenital dysplasia homolog 2; faciogenital dysplasia protein 2; t-complex distorter 2; FGD2蛋白;


背景信息:
Fgd1 gene mutations result in faciogenital dysplasia (FGDY, Aarskog syndrome),an X-linked developmental disorder that adversely affects the formation of multiple skeletal structures (1). FGD1 maps to human chromosome Xp11.21 and shares a high degree of sequence identity with the FGD2 (6p21.2) and the FGD3 (9q22) proteins (1-4). FGD1 encodes a guanine nucleotide exchange factor that specifically activates the Rho GTPase Cdc42 (1,5). FGD2 is present in several diverse tissues during embryogenesis, suggesting a role in embryonic development (2). FGD3 stimulates fibroblasts to form filopodia, which are actin microspikes formed upon the stimulation of Cdc42 (1). All FGD family members contain equivalent signaling domains and a conserved structural organization, which strongly suggests that these signaling domains form a canonical core structure for members of the FGD family of RhoGEF proteins (2). These proteins control essential signals required during embryonic development (6,7).

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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