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蛋白质/抗原/多肽 >> 重组蛋白
重组FGD3蛋白
重组FGD3蛋白图片
交货期: 1周
索取资料及报价
交货期:1周
产品别名:Recombinant Fgd3
Recombinant FYVE, RhoGEF and PH domain containing 3 protein
产品介绍
基因名:

Fgd3


产品别名:

5830461L01Rik; ZFYVE5; Fgd3; FYVE, RhoGEF and PH domain containing 3; FYVE, RhoGEF and PH domain containing 3; FYVE, RhoGEF and PH domain-containing protein 3; Fgd1 family, member 3; faciogenital dysplasia homolog 3; FGD3蛋白;


背景信息:
FGD1 gene mutations result in faciogenital dysplasia (FGDY, Aarskog-Scott syndrome), an X-linked developmental disorder that adversely affects the formation of multiple skeletal structures. FGD1 maps to human chromosome Xp11.21 and shares a high degree of sequence identity with the FGD2 (6p21.2) and the FGD3 (9q22.31) proteins. FGD1 encodes a guanine nucleotide exchange factor that specifically activates the Rho GTPase Cdc42. FGD2 is present in several diverse tissues during embryogenesis, suggesting a role in embryonic development. FGD3 stimulates fibroblasts to form filopodia, which are Actin microspikes formed upon the stimulation of Cdc42. All FGD family members contain equivalent signaling domains and a conserved structural organization, which strongly suggests that these signaling domains form a canonical core structure for members of the FGD family of RhoGEF proteins. These proteins control essential signals required during embryonic development.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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