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蛋白质/抗原/多肽 >> 重组蛋白
重组新朊蛋白
重组新朊蛋白图片
交货期: 1周
索取资料及报价
交货期:1周
产品别名:重组新朊蛋白(C端)
Recombinant Sprn
产品介绍
基因名:

Sprn


产品别名:

CG14128; Dmel\CG14128; sprn; Sprn; Spermitin; Spermitin; spermitin; CG14128-PB; CG14128-PC; CG14128-PE; CG14128-PF; Sprn-PB; Sprn-PC; Sprn-PE; Sprn-PF; 新朊蛋白; 新朊蛋白(C端);


背景信息:
Prion diseases, or transmissible spongiform encephalopathies (TSEs), are manifested as genetic, infectious or sporadic lethal neurodegenerative disorders involving alterations of the prion protein (PrP). Constitutively expressed in normal adult brain, cellular PrP (PrP(C)) is sensitive to proteinase K digestion and is converted to the disease form, PrPSc, through alterations in protein folding conformation, which make it resistant proteases. SPRN (shadow of prion protein), also known as SHO or SHADOO, is a 151 amino acid cytoplasmic protein that is mainly expressed in brain. SPRN is considered a prion-like protein that has PrP(C)-like neuroprotective activity and may act as a modulator for the biological actions of normal and abnormal PrP. In humans, mutations in the gene encoding SPRN may be associated with variant and sporadic Creutzfeldt-Jakob disease, a degenerative neurological disorder that is incurable and invariably fatal

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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