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蛋白质/抗原/多肽 >> 重组蛋白
重组癌/睾丸抗原128蛋白
重组癌/睾丸抗原128蛋白图片
交货期: 1周
索取资料及报价
交货期:1周
产品别名:Recombinant mael
Recombinant maelstrom protein
产品介绍
基因名:

mael


产品别名:

CG11254; Dmel\CG11254; MAEL; Mael; mae1; mael; maelstrom; maelstrom; maelstrom; CG11254-PA; CG11254-PB; CG11254-PC; CG11254-PD; mael-PA; mael-PB; mael-PC; mael-PD; 癌/睾丸抗原128;


背景信息:
Mael is a 434 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one HMG box DNA-binding domain. Expressed specifically in testicular tissue, Mael interacts with Ini1, mSin3B and VASA and plays an essential role in spermatogenesis, specifically by repressing and, ultimately, preventing the mobilization of transposable elements (a process that is crucial for germline integrity). Multiple isoforms of Mael exist due to alternative splicing events. The gene encoding Mael maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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