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蛋白质/抗原/多肽 >> 重组蛋白
重组跨膜蛋白48
重组跨膜蛋白48图片
交货期: 1周
索取资料及报价
交货期:1周
产品别名:Recombinant Ndc1
Recombinant Nuclear division cycle 1 protein
产品介绍
基因名:

Ndc1


产品别名:

CG5857; Dmel\CG5857; NDC1; ndc1; Ndc1; Nuclear division cycle 1; Nuclear division cycle 1; nuclear division cycle 1; CG5857-PA; Ndc1 ortholog; Ndc1-PA; 跨膜蛋白48;


背景信息:
NDC1 is a 674 amino acid multi-pass membrane protein, central core structure of the nuclear pore complex (NPC) and member of the NDC1 family that is crucial for selective nuclear protein import. Existing as four alternatively spliced isoforms that are encoded by a gene located on human chromosome 1, NDC1 interacts with Nup35 and anchors Aladin to the nuclear envelope of the NPC, a region of macromolecular transport between the nucleus and cytoplasm. In the absence of NDC1, Aladin becomes mislocalized and may lead to the development of an autosomal recessive disorder termed achalasia-addisonianism-alacrima (triple A) syndrome. Triple A syndrome is characterized by achalasia, alacrima and adrenocortico-tropin-resistant adrenal insufficiency. Robust expression in neural systems associated with cognitive, motor and sensory functions is consistent with the myriad of symptoms experienced by patients with triple A syndrome.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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