蛋白质/抗原/多肽 >> 重组蛋白
重组甘油磷酸二酯磷酸二酯酶1(GDE1)蛋白
产品介绍 基因名: GDE1 产品别名: 363E6.2; MIR16; GDE1; glycerophosphodiester phosphodiesterase 1; glycerophosphodiester phosphodiesterase 1; glycerophosphodiester phosphodiesterase 1; RGS16-interacting membrane protein; glycerophosphoinositol glycerophosphodiesterase GDE1; lysophospholipase D GDE1; membrane interacting protein of RGS16; 甘油磷酸二酯磷酸二酯酶1(GDE1); 膜蛋白GDE1(MIR16); 背景信息: GDE1 is a 331 amino acid multi-pass membrane protein that localizes to both the membrane and the cytoplasm and contains one GDPD domain. Expressed in a wide variety of tissues, GDE1 uses magnesium as a cofactor to catalyze the conversion of 1-(sn-glycero-3-phospho)-1D-myo-inositol to myo-inositol and sn-glycerol 3-phosphate, an event that is modulated by G protein signaling pathways and provides a link between phosphoinositide metabolism and G protein signal transduction. The gene encoding GDE1 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition. 标签:His-tag |
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