产品介绍 基因名: ARID4B 产品别名: BCAA; BRCAA1; RBBP1L1; RBP1L1; SAP180; ARID4B; AT-rich interaction domain 4B; AT-rich interaction domain 4B; AT-rich interactive domain-containing protein 4B; 180 kDa Sin3-associated polypeptide; ARID domain-containing protein 4B; AT rich interactive domain 4B (RBP1-like); Rb-binding protein homolog; SIN3A-associated protein 180; breast cancer-associated antigen 1; breast cancer-associated antigen BRCAA1; breast carcinoma-associated antigen; histone deacetylase complex subunit SAP180; retinoblastoma-binding protein 1-like 1; sin3-associated polypeptide p180; 乳腺癌相关抗原BRCAA1; 背景信息: This gene encodes a protein with sequence similarity to retinoblastoma-binding protein-1. The encoded protein is a subunit of the histone deacetylase-dependant SIN3A transcriptional corepressor complex, which functions in diverse cellular processes including proliferation, differentiation, apoptosis, oncogenesis, and cell fate determination. The gene product is recognized by IgG antibody isolated from a breast cancer patient and appears to be a molecular marker associated with a broad range of human malignancies. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008]. 标签:His-tag |
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