产品介绍 基因名: MARCHF5 产品别名: MARCH-V; MARCH5; MITOL; RNF153; MARCHF5; membrane associated ring-CH-type finger 5; membrane associated ring-CH-type finger 5; E3 ubiquitin-protein ligase MARCHF5; E3 ubiquitin-protein ligase MARCH5; RING-type E3 ubiquitin transferase MARCH5; RING-type E3 ubiquitin transferase MARCHF5; membrane associated ring finger 5; membrane-associated RING finger protein 5; membrane-associated RING-CH protein V; membrane-associated ring finger (C3HC4) 5; mitochondrial ubiquitin ligase; ring finger protein 153; 膜相关环指蛋白5; 背景信息: MARCH5 is a member of the E3 ubiquitin-protein ligase family. This mitochonrial E3 ubiquitin-protein ligase plays an importnat role in controlling the morphology of the mitochondria. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. MARCH5 has been shown to interact with MTFN2 and ubiquitinated forms of DRP1. 标签:His-tag |
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