蛋白质/抗原/多肽 >> 重组蛋白
重组膜相关接头蛋白LAX
产品介绍 基因名: LAX1 产品别名: LAX; LAX1; lymphocyte transmembrane adaptor 1; lymphocyte transmembrane adaptor 1; lymphocyte transmembrane adapter 1; LAT-like membrane associated protein; linker for activation of x cells; membrane-associated adapter protein LAX; 膜相关接头蛋白LAX; 背景信息: LAX1 is a 398 amino acid single-pass type III membrane protein that negatively regulates lymphocyte signaling. LAX1 is expressed in lymphoid tissues including thymus, spleen and peripheral blood leukocytes, along with several B-cell, T-cell, natural killer and monocyte cell lines. When stimulated by B or T cells, LAX1 becomes dramatically upregulated and also interacts with GRB2, Gads and PI 3-kinase p85 upon phosphorylation. LAX1 exists as two alternatively spliced isoforms that are encoded by a gene located on human chromosome 1. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. 标签:His-tag |
相关产品
|