蛋白质/抗原/多肽 >> 重组蛋白
重组ATP依赖RNA解旋酶DDX60蛋白
产品介绍 基因名: DDX60 产品别名: DDX60; DExD/H-box helicase 60; DExD/H-box helicase 60; probable ATP-dependent RNA helicase DDX60; ATP-dependent RNA helicase DDX60; DEAD (Asp-Glu-Ala-Asp) box polypeptide 60; DEAD box protein 60; DEAD-box helicase 60; ATP依赖RNA解旋酶DDX60; 背景信息: DDX60 is a 1,712 amino acid protein belonging to the helicase family. DDX60 contains one helicase ATP-binding domain and one helicase C-terminal domain. The gene encoding DDX60 maps to human chromosome 4, which represents approximately 6% of the human genome and contains nearly 900 genes. Notably, the Huntington gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is on chromosome 4. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease. Chromosome 4 reportedly contains the largest gene deserts (regions of the genome with no protein encoding genes) and has one of the two lowest recombination frequencies of the human chromosomes. 标签:His-tag |
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