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蛋白质/抗原/多肽 >> 重组蛋白
重组Rho GTP酶激活蛋白15
重组Rho GTP酶激活蛋白15图片
交货期: 1周
索取资料及报价
交货期:1周
产品别名:Recombinant ARHGAP15
Recombinant Rho GTPase activating protein 15 protein
产品介绍
基因名:

ARHGAP15


产品别名:

BM046; ARHGAP15; Rho GTPase activating protein 15; Rho GTPase activating protein 15; rho GTPase-activating protein 15; rho-type GTPase-activating protein 15; Rho GTP酶激活蛋白15;


背景信息:
Rho GTPases, which play fundamental roles in numerous cellular processes, are initiated by external stimuli that signal though G-protein coupled receptors. ARHGEF15 (Rho guanine nucleotide exchange factor (GEF) 15), also known as ARGEF15 or Vsm-RhoGEF, is a 841 amino acid protein expressed in the vascular smooth muscle of coronary artery. ARHGEF15 functions as a specific guanine nucleotide exchange factor for RhoA and interacts with ephrin-A4 in vascular smooth muscle cells. Containing one DH (DBL-homology) domain, ARHGEF15 is phosphorylated on tyrosine residues upon ephrin-A1 stimulation. The DH domain consists of a region of about 150 amino acids that induces Rho family GTPases to release GDP. This effectively activates the Rho GTPase by allowing GTP binding. ARHGEF15 is encoded by a gene located on human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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