蛋白质/抗原/多肽 >> 重组蛋白
重组8号染色体开放阅读框4蛋白
产品介绍 基因名: TCIM 产品别名: C8orf4; TC-1; TC1; TCIM; transcriptional and immune response regulator; transcriptional and immune response regulator; transcriptional and immune response regulator; human thyroid cancer 1; protein C8orf4; thyroid cancer protein 1; 8号染色体开放阅读框4; 背景信息: This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies. [provided by RefSeq, Nov 2011] 标签:His-tag |
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