产品介绍 基因名: BMAL2 产品别名: ARNTL2; CLIF; MOP9; PASD9; bHLHe6; BMAL2; basic helix-loop-helix ARNT like 2; basic helix-loop-helix ARNT like 2; aryl hydrocarbon receptor nuclear translocator-like protein 2; CYCLE-like factor; PAS domain-containing protein 9; aryl hydrocarbon receptor nuclear translocator like 2; basic-helix-loop-helix-PAS protein MOP9; brain and muscle ARNT-like 2; class E basic helix-loop-helix protein 6; member of PAS protein 9; member of PAS superfamily 9; transcription factor BMAL2; 芳香烃受体核转录蛋白样2; 背景信息: BMAL2 is a 636 amino acid protein that localizes to the nucleus and contains one bHLH (basic helix-loop-helix) domain, one PAC (PAS-associated C-terminal) domain and two PAS (PER-ARNT-SIM) domains. Expressed at high levels in placenta and brain and at lower levels in liver, thymus, heart, lung and kidney, BMAL2 functions as a component of the circadian core oscillator, which includes a variety of proteins that work in tandem to activate the transcription of target genes. More specifically, BMAL2, when functioning as a component of the core oscillator, binds to the E-box element (3'-CACGTG-5') of target DNA, thus inducing transcription. Multiple isoforms of BMAL2 exist due to alternative splicing events. 标签:His-tag |
相关产品
|