蛋白质/抗原/多肽 >> 重组蛋白
重组慢性淋巴细胞白血病缺失基因6蛋白
产品介绍 基因名: SPRYD7 产品别名: C13orf1; CLLD6; SPRYD7; SPRY domain containing 7; SPRY domain containing 7; SPRY domain-containing protein 7; CLL deletion region gene 6 protein; chronic lymphocytic leukemia deletion region gene 6 protein; epididymis secretory sperm binding protein; 慢性淋巴细胞白血病缺失基因6蛋白; 背景信息: CLLD6, is a 196 amino acid protein that contains one B30.2/SPRY domain. Expression of CLLD6 is found at highest levels in heart, skeletal muscle and testis, with lower levels found in thymus, peripheral blood leukocytes, lymph node and bone marrow. Existing as two alternatively spliced isoforms, CLLD6 maps to human chromosome 13, which comprises nearly 4% of human DNA and contains about 114 million base pairs and 400 genes. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. RB1 encodes a crucial tumor suppressor protein which, when defective, leads to malignant growth in the retina and has been implicated in a variety of other cancers. The gene SLITRK1, which is associated with Tourette syndrome, is on chromosome 13. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival. 标签:His-tag |
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