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蛋白质/抗原/多肽 >> 重组蛋白
重组肥大细胞膜抑制性受体Allergin1蛋白
重组肥大细胞膜抑制性受体Allergin1蛋白图片
交货期: 1周
索取资料及报价
交货期:1周
产品别名:Recombinant Milr1
Recombinant mast cell immunoglobulin-like receptor 1 protein
产品介绍
基因名:

Milr1


产品别名:

Mca32; Milr1; mast cell immunoglobulin-like receptor 1; mast cell immunoglobulin-like receptor 1; allergin-1; MCA-32; allergy inhibitory receptor 1; mast cell Ag-32; mast cell antigen 32; surface protein MCA-32; 肥大细胞膜抑制性受体Allergin1;


背景信息:
As a major event in type Ⅰ allergic reaction,degranulation of mast cells is triggered by the interaction between specific IgEs and high affinity IgE receptors (FcεRIs) on mast cell membrane,and is followed by the release of a battery of inflammatory mediators,such as histamine,leukotrienes and arachidonic acid,and these inflammatory mediators in turn induce a series of allergic symptoms.Recently,Allergin-1 has been found to be an immunoglobulin-like receptor preferentially expressed on mast cells.The crosslinking of Allergin-1 to FcεRIs on mast cells may inhibit the signal transduction from FcεRIs to intracellular immunoreceptor tyrosine-based inhibitory motif (ITIM),generate ITIM inhibitory signals,which then participate in the regulation of mast cell degranulation,and finally block the initiation of allergic inflammation.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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