蛋白质/抗原/多肽 >> 重组蛋白
重组信号肽复合物亚基3蛋白
产品介绍 基因名: SPCS3 产品别名: PRO3567; SPC22; SPC22/23; SPC23; SPC3; YLR066W; SPCS3; signal peptidase complex subunit 3; signal peptidase complex subunit 3; signal peptidase complex subunit 3; SPase 22 kDa subunit; SPase 22/23 kDa subunit; microsomal signal peptidase 22/23 kDa subunit; microsomal signal peptidase 23 kDa subunit; signal peptidase complex subunit 3 homolog; 信号肽复合物亚基3; 背景信息: SPCS3 (signal peptidase complex subunit 3), also known as SPC3, is a 180 amino acid single-pass type II membrane protein that localizes to both the microsome and the endoplasmic reticulum (ER) and belongs to the SPCS (signal peptidase complex subunit) family. Existing as a component of the microsomal signal peptidase complex which consists of five members, SPCS3 functions to remove signal peptides from proteins that are translated to the lumen of the ER. The gene encoding SPCS3 maps to human chromosome 4, which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease. 标签:His-tag |
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