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蛋白质/抗原/多肽 >> 重组蛋白
重组中心体肌动蛋白γ1/增强型PI3K蛋白
重组中心体肌动蛋白γ1/增强型PI3K蛋白图片
交货期: 1周
索取资料及报价
交货期:1周
产品别名:Recombinant Agap2
Recombinant ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 protein
产品介绍
基因名:

Agap2


产品别名:

Centg1; Pike; Agap2; ArfGAP with GTPase domain, ankyrin repeat and PH domain 2; ArfGAP with GTPase domain, ankyrin repeat and PH domain 2; arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2; AGAP-2; centaurin, gamma 1; cnt-g1; nuclear GTPase PIKE; phosphatidylinositol 3-kinase enhancer; 中心体肌动蛋白γ1/增强型PI3K蛋白;


背景信息:
GTPase-activating protein (GAP) for ARF1 and ARF5, which also shows strong GTPase activity. Isoform 1 participates in the prevention of neuronal apoptosis by enhancing PI3 kinase activity. It aids the coupling of metabotropic glutamate receptor 1 (GRM1) to cytoplasmic PI3 kinase by interacting with Homer scaffolding proteins, and also seems to mediate anti-apoptotic effects of NGF by activating nuclear PI3 kinase. Isoform 2 does not stimulate PI3 kinase but may protect cells from apoptosis by stimulating Akt. It also regulates the adapter protein 1 (AP-1)-dependent trafficking of proteins in the endosomal system. It seems to be oncogenic. It is overexpressed in cancer cells, prevents apoptosis and promotes cancer cell invasion.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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