蛋白质/抗原/多肽 >> 重组蛋白
重组F-box蛋白相关蛋白36
产品介绍 基因名: Fbxo36 产品别名: 0610008D19Rik; 1110020F21Rik; 2410002G19Rik; D1Ertd757e; Fbxo36; F-box protein 36; F-box protein 36; F-box only protein 36; F-box蛋白相关蛋白36; 背景信息: FBXO36 is a 188 amino acid protein that contains one forty amino acid F-box region, making it a member of the F-box family. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. F-box proteins are members of a large family that regulates cell cycle, immune response, signaling cascades and developmental programs by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, IkB-? and ∫-catenin, for degradation by the proteasome after ubiquitination. Functioning as a component of the SCF complex, FBXO36 is thought to recognize and bind to select phosphorylated proteins, thereby promoting their ubiquitination and subsequent degradation. 标签:His-tag |
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