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蛋白质/抗原/多肽 >> 重组蛋白
重组双氧化酶激活因子2蛋白
重组双氧化酶激活因子2蛋白图片
交货期: 1周
索取资料及报价
交货期:1周
产品别名:Recombinant Duoxa2
Recombinant dual oxidase maturation factor 2 protein
产品介绍
基因名:

Duoxa2


产品别名:

9030623N16Rik; Nip2; Duoxa2; dual oxidase maturation factor 2; dual oxidase maturation factor 2; dual oxidase maturation factor 2; Numb-interacting protein 2; 双氧化酶激活因子2;


背景信息:
DUOXA2 is a 320 amino acid multi-pass membrane protein that localizes to the endoplasmic reticulum (ER) and belongs to the DUOXA family. Expressed specifically in thyroid and salivary glands, DUOXA2 is essential for the maturation and transport of DUOX2 from the ER to the plasma membrane and is also thought to play a role in the synthesis of thyroid hormone (TH). Defects in the DUOXA2 gene are associated with the pathogenesis of congenital hypothyroidism, a disorder that affects infants and is characterized by a significant decrease or a complete deficiency of TH from birth. The gene encoding DUOXA2 maps to human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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