蛋白质/抗原/多肽 >> 重组蛋白
重组序列相似家族132成员A(FAM132A)蛋白
产品介绍 基因名: C1qtnf12 产品别名: 1110035L05Rik; C1qdc2; CTRP12; Fam132a; alipolin; C1qtnf12; C1q and tumor necrosis factor related 12; C1q and tumor necrosis factor related 12; adipolin; C1q domain containing 2; adipose-derived insulin-sensitizing factor; complement C1q tumor necrosis factor-related protein 12; family with sequence similarity 132, member A; protein FAM132A; 序列相似家族132成员A(FAM132A); 脂肪源性胰岛素增敏因子; 背景信息: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The FAM132A gene product has been provisionally designated FAM132A pending further characterization. 标签:His-tag |
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