蛋白质/抗原/多肽 >> 重组蛋白
重组脱磷酸辅酶A结构域蛋白
产品介绍 基因名: Dcakd 产品别名: 3010024O21Rik; 6720485C15Rik; AI849483; Dcakd; dephospho-CoA kinase domain containing; dephospho-CoA kinase domain containing; dephospho-CoA kinase domain-containing protein; 脱磷酸辅酶A结构域蛋白; 背景信息: DCAKD belongs to the coaE family. It contains one DPCK (dephospho CoA kinase) domain. There are two isoforms.Coenzyme A (CoA) is an essential cofactor used in numerous biochemical pathways. It plays a critical role in the synthesis and oxidation of fatty acids and is vital to the citric acid cycle. The biosynthesis pathway of CoA from pantothenic acid (also known as vitamin B5) is essential and universal in prokaryotes and eukaryotes. In humans, the final steps of the biosynthesis pathway are carried out by the bifunctional enzyme COASY. The sequence of these enzymes are highly conserved between different bacterial species. The phosphopantetheine adenylyltransferase and dephospho-coenzyme A kinase activities of COASY are evolutionarily conserved activities. DCAKD (dephospho-CoA kinase domain containing protein) is a 231 amino acid protein that consists of a dephospho-CoA kinase domain and an ATP nucleotide binding motif. Localizing to mitochondria and the cytosol, DCAKD belongs to the coaE family which suggests that it may play a role in the biosynthesis of CoA. 标签:His-tag |
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