产品介绍 基因名: Dhrs13 产品别名: 2610209N15Rik; Dhrs13; dehydrogenase/reductase (SDR family) member 13; dehydrogenase/reductase (SDR family) member 13; dehydrogenase/reductase SDR family member 13; androgen-regulated short-chain dehydrogenase/reductase 1; prostate short-chain dehydrogenase reductase 1; likely ortholog of mouse cell line MC/9.IL4 derived transcript 1; CGI-82 protein; HCV core-binding protein; short chain dehydrogenase/reductase family 7C member 5; 短链脱氢还原酶13; 背景信息: DHRS13 (dehydrogenase/reductase SDR family member 13), also known as UNQ419/PRO853, is a 377 amino acid secreted protein belonging to the short-chain dehydrogenases/reductases (SDR) family. DHRS13 is presumed to function as an oxidoreductase and is phosphorylated, potentially by ATM or ATR, upon DNA damage. DHRS13 exists as two isoforms produced by alternative splicing events. The gene encoding DHRS13 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Neurofibromatosis, dysregulated Schwann cell growth, Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are associated with chromosome 17. 标签:His-tag |
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