蛋白质/抗原/多肽 >> 重组蛋白
重组锌指蛋白340
产品介绍 基因名: Zbtb46 产品别名: 2610019F01Rik; 4933406L05Rik; BZEL; Btbd4; Zbtb46; zinc finger and BTB domain containing 46; zinc finger and BTB domain containing 46; zinc finger and BTB domain-containing protein 46; BTB (POZ) domain containing 4; BTB-ZF protein expressed in effector lymphocytes; BTB/POZ domain-containing protein 4; 锌指蛋白340; 背景信息: BTBD4 is a 589 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD4 may play a role in transcription regulation. 标签:His-tag |
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