蛋白质/抗原/多肽 >> 重组蛋白
重组ELMO3蛋白
产品介绍 基因名: ELMO3 产品别名: CED-12; CED12; ELMO-3; ELMO3; engulfment and cell motility 3; engulfment and cell motility 3; engulfment and cell motility protein 3; ced-12 homolog 3; ELMO3蛋白; 吞噬/细胞运动因子3(ELMO3); 背景信息: Elmo1 associates with DOCK 180 and may influence phagocytosis and effect cell shape changes. Src family kinase mediated tyrosine phosphorylation of ELMO1 influences signaling through Elmo1/Crk/DOCK 180 pathways. Elmo2 interacts directly with Rho G in a GTP-dependent manner and forms a ternary complex with DOCK 180 to induce activation of Rac 1. The RhoG-Elmo2-DOCK 180 pathway is required for activation of Rac 1 and cell spreading mediated by integrin, as well as for neurite outgrowth induced by nerve growth factor. Elmo3 acts in assocation with DOCK180 and Crk II and may be required in complex with DOCK180 to activate Rac/Rho small GTPases. 标签:His-tag |
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