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蛋白质/抗原/多肽 >> 重组蛋白
重组上皮钙粘附分子结合蛋白E7
重组上皮钙粘附分子结合蛋白E7图片
交货期: 1周
索取资料及报价
交货期:1周
产品别名:Recombinant CBLL1
Recombinant Cbl proto-oncogene like 1 protein
产品介绍
基因名:

CBLL1


产品别名:

HAKAI; RNF188; CBLL1; Cbl proto-oncogene like 1; Cbl proto-oncogene like 1; E3 ubiquitin-protein ligase Hakai; Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1; Cbl proto-oncogene like 1, E3 ubiquitin protein ligase; Cbl proto-oncogene, E3 ubiquitin protein ligase-like 1; E-cadherin binding protein E7; RING finger protein 188; RING-type E3 ubiquitin transferase Hakai; c-Cbl-like protein 1; casitas B-lineage lymphoma-transforming sequence-like protein 1; 上皮钙粘附分子结合蛋白E7;


背景信息:
CBLL1, also known as HAKAI (meaning ‘destruction’ in Japanese), or RNF188 (RING finger protein 188), is a 491 amino acid protein that contains one C2H2-type zinc finger and one RING-type zinc finger. CBLL1 is believed to function as an E3 ubiquitin-protein ligase that accepts a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfers that residue to a protein that is targeted for degradation. More specifically, upon activation of c-Src, CBLL1 interacts with and ubiquitinates tyrosine-phosphorylated E-cadherin, thereby targeting the E-cadherin complex for endocytosis and disrupting epithelial cell-cell contacts. Via its role as an E-cadherin regulator, CBLL1 participates in cell adhesion and may also be involved in the regulation of epithelial-mesenchymal transitions.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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