蛋白质/抗原/多肽 >> 重组蛋白
重组脑低密度脂蛋白受体蛋白1
产品介绍 基因名: NETO1 产品别名: BCTL1; BTCL1; NETO1; neuropilin and tolloid like 1; neuropilin and tolloid like 1; neuropilin and tolloid-like protein 1; brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1; neuropilin (NRP) and tolloid (TLL)-like 1; 脑低密度脂蛋白受体蛋白1; 背景信息: NETO1 is a 533 amino acid protein that contains one LDL-receptor class A domain and two CUB domains and is either membrane-bound or secreted. Expressed as three alternatively spliced isoforms, the first two of which are retina-specific and the third of which is found in both retina and brain tissue, NETO1 is thought to be involved in the development and maintenance of neuronal circuitry, possibly playing a role in proper brain function. Human NETO1 shares 95% amino acid identity with its mouse counterpart, suggesting a conserved role between species. The gene encoding NETO1 maps to human chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases. There are a variety of diseases associated with defects in chromosome 18-localized genes, some of which include Trisomy 18 (also known as Edwards syndrome), Niemann-Pick disease, hereditary hemorrhagic telangiectasia, erythropoietic protoporphyria and follicular lymphomas. 标签:His-tag |
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