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重组低密度脂蛋白受体5样蛋白
重组低密度脂蛋白受体5样蛋白图片
交货期: 1周
索取资料及报价
交货期:1周
产品别名:重组低密度脂蛋白受体相关蛋白5样蛋白(LRP5L)
Recombinant LRP5L
产品介绍
基因名:

LRP5L


产品别名:

LRP5L; LDL receptor related protein 5 like (pseudogene); LDL receptor related protein 5 like (pseudogene); LRP-5-like; low density lipoprotein receptor-related protein 5-like; low-density lipoprotein receptor-related protein 5-like protein; 低密度脂蛋白受体5样蛋白; 低密度脂蛋白受体相关蛋白5样蛋白(LRP5L);


背景信息:
Members of the LDL receptor gene family, including LDLR (low density lipo-protein receptor), LRPs (low density lipoprotein related proteins), Megalin (also designated GP330), VLDLR (very low density lipoprotein receptor) and ApoER2, are characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. Of the known family members, LRP5 is most closely related to LRP1. However, LRP5 has a unique organization of EGF and LDLR repeats compared to other LDLR family members and likely represents a new category in this family. LRP is expressed in rat tibia, specifically in areas of the bone that are involved in remodeling. LRP5 is a Wnt coreceptor that binds to Axin and regulates the canonical Wnt signaling pathway. LRP5 affects bone mass accrual during growth. Mutations in LRP5 cause the autosomal recessive disorder osteoporosis-pseudoglioma syndrome (OPPG). LRP5L is a related protein that exists as two isoforms produced by alternative splicing.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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