蛋白质/抗原/多肽 >> 重组蛋白
重组染色质修饰蛋白CHMP7
产品介绍 基因名: CHMP7 产品别名: CHMP7; charged multivesicular body protein 7; charged multivesicular body protein 7; charged multivesicular body protein 7; CHMP family, member 7; chromatin-modifying protein 7; 染色质修饰蛋白CHMP7; 背景信息: The charged multivesicular body proteins or chromatin modifying proteins, commonly designated CHMPs, belong to the vacuolar sorting protein family and function as chromatin-modifying proteins. CHMP1-6 are all components of ESCRT (endosomal sorting complex required for transport) I, II or III complexes. These complexes are crucial for sorting endosomal articles into multivesicular bodies (MVBs), as well as required for the formation of these bodies. CHMP7 is an ESCRT-III-related protein that associates with CHMP4B. CHMP7 contains an SNF7 domain in the C-terminus and is most similar to CHMP6. CHMP7 also binds to the microtubule interacting and transport (MIT) domain of the deubiquitinating enzyme, UBPY. The overexpression of CHMP7 inhibits EGFR degradation. 标签:His-tag |
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