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蛋白质/抗原/多肽 >> 重组蛋白
重组核组装因子1核糖核蛋白
重组核组装因子1核糖核蛋白图片
交货期: 1周
索取资料及报价
交货期:1周
产品别名:Recombinant NAF1
Recombinant nuclear assembly factor 1 ribonucleoprotein protein
产品介绍
基因名:

NAF1


产品别名:

NAF1; nuclear assembly factor 1 ribonucleoprotein; nuclear assembly factor 1 ribonucleoprotein; H/ACA ribonucleoprotein complex non-core subunit NAF1; nuclear assembly factor 1 homolog; 核组装因子1核糖核蛋白;


背景信息:
NAF1 is a 494 amino acid RNA-binding protein belonging to the NAF1 family. Encoded by a gene that maps to human chromosome 4q32.2, NAF1 associates with mature RNA in cell lysates and is essential for ribosome biogenesis, premessenger RNA splicing, stable RNA accumulation, maturation of box snoRNP complexes and telomere maintenance. NAF1 mobilizes at the site of transcription where it binds to and escorts the core protein Dyskerin between the nucleus and cytoplasm. NAF1 is replaced by GAR1, which binds competitively with NAF1, resulting in mature RNPs in Cajal bodies and nucleoli. NAF1 delocalizes to the cytoplasm during overexpression but NAF1 shuttling properties continue to be operative. Dyskeratosis congenita mutations in human telomerase RNA may affect NAF1 assembly function.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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