产品介绍 基因名: Slc9b2 产品别名: C80638; NHA2; NHE10; Nhedc2; nha-oc; nhaoc; Slc9b2; solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2; solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2; sodium/hydrogen exchanger 9B2; NHE domain-containing protein 2; Na(+)/H(+) exchanger NHA2; Na(+)/H(+) exchanger-like domain-containing protein 2; Na+/H+ exchanger domain containing 2; mitochondrial Na(+)/H(+) exchanger NHA2; mitochondrial sodium/hydrogen exchanger 9B2; mitochondrial sodium/hydrogen exchanger NHA2; soditlum/hydrogen exchanger-like domain-containing protein 2; sodium/hydrogen exchanger-like domain-containing protein 2; solute carrier family 9 subfamily B member 2; 线粒体钠/氢交换蛋白质2; 背景信息: Na+/H+ exchangers (NHEs) catalyze the transport of Na+ in exchange for H+ across membranes in organisms and are required for numerous physiological processes. NHEDC2 (Na+/H+ exchanger-like domain-containing protein 2), also known as NHA2, is a 537 amino acid mitochondrial protein. NHEDC2 is involved in organelle volume homeostasis by catalyzing the exchange of protons for Na+ and Li+ across the inner mitochondrial membrane. Found in red blood cells, NHEDC2 is required for bone resorption activity and osteoclast differentiation. As a multi-pass membrane protein, NHEDC2 is expressed as two isoforms produced by alternative splicing events. 标签:His-tag |
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