蛋白质/抗原/多肽 >> 重组蛋白
重组11号染色体开放阅读框46蛋白
产品介绍 基因名: ARL14EP 产品别名: ARF7EP; C11orf46; dJ299F11.1; ARL14EP; ADP ribosylation factor like GTPase 14 effector protein; ADP ribosylation factor like GTPase 14 effector protein; ARL14 effector protein; ADP-ribosylation factor-like 14 effector protein; ARF7 effector protein; 11号染色体开放阅读框46; 背景信息: C11orf46, also known as FLJ38968 or dJ299F11.1, is a 260 amino acid protein that is encoded by a gene located on human chromosome 11. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and β thalassemia are caused by HBB gene mutations. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11. 标签:His-tag |
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